What is the Triple Marker Test?
The Triple Marker Test, also known as the Triple Screen Test or Multiple Marker Test, is a blood test performed during pregnancy to assess the risk of certain chromosomal abnormalities and neural tube defects in the developing fetus. It measures three specific substances in the mother’s blood:

1. Alpha-fetoprotein (AFP) – a protein produced by the fetus.
2. Human chorionic gonadotropin (hCG) – a hormone produced by the placenta.
3. Estriol (uE3) – an estrogen produced by both the fetus and the placenta.

The test is typically performed between the 15th and 20th week of pregnancy, with optimal results usually around the 16th to 18th week.

Purpose of the Triple Marker Test:

1. Screening for Chromosomal Abnormalities:

   • It assesses the risk of the fetus having chromosomal conditions like Down syndrome (Trisomy 21) and Edward’s syndrome (Trisomy 18).

2. Detecting Neural Tube Defects:

   • It helps in identifying neural tube defects such as spina bifida or anencephaly, which are birth defects affecting the brain and spine.

3. Monitoring Fetal Health:

   • While it’s not a diagnostic test, it provides a risk assessment that, when combined with other factors (maternal age, ultrasound findings, etc.), helps healthcare providers determine if further testing, such as amniocentesis or chorionic villus sampling (CVS), is needed.

Substances Measured in the Test:

1. Alpha-fetoprotein (AFP):

   • High levels may indicate neural tube defects.
   • Low levels can be associated with Down syndrome.

2. Human Chorionic Gonadotropin (hCG):

   • Elevated levels can indicate a higher risk of Down syndrome.

3. Estriol (uE3):

   • Low levels of estriol may indicate a risk for Down syndrome or other chromosomal abnormalities.

When is the Triple Marker Test Performed?
This test is performed between the 15th and 20th week of pregnancy, preferably between the 16th and 18th week. It is part of standard prenatal screening.

Who Should Get the Triple Marker Test?

• Pregnant women over the age of 35 (as the risk of chromosomal abnormalities increases with maternal age).
• Women with a family history of birth defects.
• Those who had diabetes before pregnancy.
• Women who have had previous pregnancies with chromosomal abnormalities.
• Women who have used medications or substances during pregnancy that may increase the risk of birth defects.

Sample Type:
Blood sample (SERUM).

Preparation for the Test:

• Fasting: No fasting is required for this test.
• Medications: Inform your healthcare provider of any medications you are taking, as some medications can affect the results.

How the Test Works:

1. A blood sample is drawn from a vein in your arm.
2. The sample is analyzed to measure the levels of AFP, hCG, and estriol in the mother’s blood.
3. The results are interpreted along with the mother’s age, weight, ethnicity, and the stage of pregnancy to determine the risk level for certain fetal abnormalities.

Interpretation of Results:

• High Risk: If the test results show abnormal levels of the three substances, it indicates a higher risk for conditions such as Down syndrome, Trisomy 18, or neural tube defects. However, this does not confirm the diagnosis. Further diagnostic tests may be recommended.
• Low Risk: Normal levels of these markers generally suggest a lower risk of the aforementioned conditions, but it does not guarantee the absence of birth defects.

SpeedDiagno Booking and Collection:

• Book Easily: Schedule your Triple Marker Test through the SpeedDiagno app or website.
• Fast Sample Collection: SpeedDiagno offers rapid sample collection services, often within minutes of booking, depending on your location and availability.
• At-Home Service: A phlebotomist can visit your home for a hassle-free sample collection.

Turnaround Time:

• Sample Collection: The blood draw takes only a few minutes.
• Results: Typically available within 2-3 days, with results accessible through the SpeedDiagno app or website.

Why Choose SpeedDiagno?

• Convenient Scheduling: Easily book your test online or via the app.
• Fast, Reliable Service: SpeedDiagno ensures quick and professional sample collection from the comfort of your home.
• Accurate Testing: All tests are processed by NABL certified labs, ensuring high standards and accuracy.
• Secure Access: Get your test results directly on the SpeedDiagno platform.

Consultation:
After receiving your results, it’s essential to discuss them with your healthcare provider to understand the findings and decide whether further testing is necessary.

Support:
For any questions or assistance, contact SpeedDiagno’s customer support.